Recombinant humaan IL-2R gamma/IL2RG-eiwit

IL2RG, also known as Interleukin-2 receptor common subunit gamma, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors. This protein is located on the surface of immature blood-forming cells in bone marrow. One end of the protein resides outside of the cell where it binds to cytokines and the other end of the protein resides in the interior of the cell where it transmits signals to the cell's nucleus. The common gamma chain partners with other proteins to direct blood-forming cells to form lymphocytes. It also directs the growth and maturation of lymphocyte subtypes. These cells kill viruses, make antibodies, and help regulate the entire immune system. Recombinant human IL2RG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 2 receptor subunit gamma, Cytokine receptor common subunit gamma, Severe combined immunodeficiency, Combined immunodeficiency X-linked, Interleukin 2 receptor gamma, IL-2 receptor subunit gamma, gammaC, p64, CD132

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

29kDa (246aa)

Common g, IL2RG, ATGP3069-10 µg, ATGP3069-20 µg, ATGP3069-50 µg, ATGP3069-100 µg, ATGP3069-250 µg, ATGP3069-500 µg, ATGP3069-1 mg, ATGP3069-10, ATGP3069-20, ATGP3069-50, ATGP3069-100, ATGP3069-250, ATGP3069-500, ATGP3069-1

Wang X. et al. (2005) . Science. 310:1159-1163.; ; Russell SM. et al. (1993) . Science. 262:1880-1883.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Hormones & Cytokines

NP_000197

P31785

Human