Recombinant humaan IL-3R alfa/IL3RA-eiwit

IL3RA, also known as interleukin 3 receptor subunit alpha isoform 1, is a single-pass type 1 membrane protein which belongs to the type 1 cytokine receptor family and type 5 subfamily. This protein is a pleiotropic cytokine produced primarily by activated T cells or mast cells. Also, the specific alpha subunit of the interleukin 3 receptor is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. Recombinant human IL3RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 3 receptor subunit alpha isoform 1, IL3RA, CD123, hIL-3Ra, IL3R

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

34.1 kDa (295aa)

Interleukin-3 receptor subunit alpha isoform 1, Interleukin3 receptor subunit alpha isoform 1, Interleukin 3 receptor subunit alpha isoform 1, IL3RY, IL3RX, IL3RAY, IL3RA, IL3R, hIL-3Ra, Hil3Ra, Hil 3Ra, CD123, ATGP3712-10 µg, ATGP3712-20 µg, ATGP3712-50 µg, ATGP3712-100 µg, ATGP3712-250 µg, ATGP3712-500 µg, ATGP3712-1 mg, ATGP3712-010, ATGP3712-020, ATGP3712-050, ATGP3712-100, ATGP3712-250, ATGP3712-500, ATGP3712-01M

Kosugi H., et al, (1995) Biochem. Biophys. Res. Commun. 208:360-367.; ; Yoshimura A., et al, (1995) EMBO J. 14:2816-2826.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_002174

P26951

Human

Ala

KEDPNPP ITNLRMKAKA QQLTWDLNRN VTDIECVKDA DYSMPAVNNS YCQFGAISLC EVTNYTVRVA NPPFSTWILF PENSGKPWAG AENLTCWIHD VDFLSCSWAV GPGAPADVQY DLYLNVANRR QQYECLHYKT DAQGTRIGCR FDDISRLSSG SQSSHILVRG RSAAFGIPCT DKFVVFSQIE ILTPPNMTAK CNKTHSFMHW KMRSHFNRKF RYELQIQKRM QPVITEQVRD RTSFQLLNPG TYTVQIRARE RVYEFLSAWS TPQRFECDQE EGANTRAWR