Recombinant humaan IL-4 eiwit

IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.

Human IL-4 stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤0.6 ng/mL.

Pitrakinra, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin 4, IL-4, BSF1, Binetrakin, BCGF1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF

E.coli

Human

Non-Tagged

SDS-PAGE, Bioactivity

1 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6 ng/mL.

15 kDa (130aa)

Pitrakinra, Pitrakinara, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin-4, Interleukin4, Interleukin 4 isoform 1, Interleukin 4, IL-4, IL4, IL 4, BSF-1, BSF1, BSF 1, Binetrakin, BCGF-1, BCGF1, BCGF 1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF, B cell stimulatory factor 1, B cell growth factor 1, ATGP3421-10 µg, ATGP3421-20 µg, ATGP3421-50 µg, ATGP3421-100 µg, ATGP3421-250 µg, ATGP3421-500 µg, ATGP3421-1 mg, ATGP3421-010, ATGP3421-020, ATGP3421-050, ATGP3421-100, ATGP3421-250, ATGP3421-500, ATGP3421-01M

Van Kimmenade A., et al (1988) . Eur J Biochem. 173 (1) : 109-14; ; Yokota T., et al (1986) . Proc. Nati. Acad. Sci. USA. 83 (16) : 5894-8;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_000580.1

P05112

Human

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