Recombinant humaan IL-7R alfa/IL7R eiwit

IL7R, also known as interleukin-7 receptor, is a hematopoietin receptor superfamily member. It plays important role in lymphocyte differentiation, proliferation, multiple sclerosis, and survival. This protein signaling is essential for T-cell development and regulation of native and memory T-cell homeostasis. Also, it is critically required for the proper development and function of lymphoid cells. Recombinant human IL7R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Interleukin 7 receptor, Interleukin-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127, CDw127, lnc-IL7R

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

52.5 kDa (461aa)

IL7 R a, CD127, ATGP3703-10 µg, ATGP3703-20 µg, ATGP3703-50 µg, ATGP3703-100 µg, ATGP3703-250 µg, ATGP3703-500 µg, ATGP3703-1 mg, ATGP3703-10, ATGP3703-20, ATGP3703-50, ATGP3703-100, ATGP3703-250, ATGP3703-500, ATGP3703-1

Goodwin RG., et al, (1990) Cell 60:941-951.; ; Melao A., et al, (2016) Haematologica 101:1368-1379.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

NP_002176

P16871

Human

Ala

ESGYAQN GDLEDAELDD YSFSCYSQLE VNGSQHSLTC AFEDPDVNIT NLEFEICGAL VEVKCLNFRK LQEIYFIETK KFLLIGKSNI CVKVGEKSLT CKKIDLTTIV KPEAPFDLSV VYREGANDFV VTFNTSHLQK KYVKVLMHDV AYRQEKDENK WTHVNLSSTK LTLLQRKLQP AAMYEIKVRS IPDHYFKGFW SEWSPSYYFR TPEINNSSGE MD