Recombinant humaan IL10R-eiwit met C-terminaal humaan Fc-tag

Expression Host : HEK293 The protein has a predicted molecular mass of 49.06 kDa after removal of the signal peptide. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Delivery in 4-6 weeks

Store at -80°C for 12 months (Avoid repeated freezing and thawing)