Recombinant humaan IL5 eiwit, hFc-tag

Molecular Characterization: IL5 (Ile20-Ser134) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of IL5-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human IL5 protein with C-terminal human Fc tagThis gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

IL-5, TRF, Interleukin-5, EDF

P05113

IL5

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.