Recombinant humaan IRF5-eiwit

IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Interferon regulatory factor 5 isoform b, SLEB10

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

10.7 kDa (101aa) confirmed by MALDI-TOF

IRF5, interferon regulatory factor 5 isoform b, SLEB10, ATGP2617-10 µg, ATGP2617-20 µg, ATGP2617-50 µg, ATGP2617-100 µg, ATGP2617-250 µg, ATGP2617-500 µg, ATGP2617-1 mg, ATGP2617-10, ATGP2617-20, ATGP2617-50, ATGP2617-100, ATGP2617-250, ATGP2617-500, ATGP2617-1

Barnes B.J., et al (2001) . J. Biol. Chem. 276:23382-23390; ; Schoenemeyer A., et al (2005) . J. Biol. Chem. 280:17005-17012;

Yeon SI, et al. Development of monoclonal antibodies against human IRF-5 and their use in identifying the binding of IRF-5 to nuclear import proteins karyopherin-alpha1 and -beta1. Yonsei Med J. 2008 Dec 31;49 (6) :1023-31.{https://pubmed.ncbi.nlm.nih.gov/19108028/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Epigenomics (Transcription & Translation)

NP_116032.1

Q13568

Human

PPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I