Recombinant humaan ITGB1BP3-eiwit

Nicotinamide riboside kinase 2, also known as ITGB1BP3, belongs to the uridine kinase family and NRK subfamily. ITGB1BP3 is found at lower levels in heart and is downregulated during myoblast differentiation. ITGB1BP3 catalyzes the phosphorylation of nicotinic acid riboside and nicotinamide riboside to form nicotinic acid mononucleotide and nicotinamide mononucleotide. Recombinant human ITGB1BP3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Nicotinamide riboside kinase 2, MIBP, NRK2

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

28.4 kDa (253aa) confirmed by MALDI-TOF

ITGB1BP3, Nicotinamide riboside kinase 2, MIBP, NRK2, ATGP1670-10 µg, ATGP1670-20 µg, ATGP1670-50 µg, ATGP1670-100 µg, ATGP1670-250 µg, ATGP1670-500 µg, ATGP1670-1 mg, ATGP1670-10, ATGP1670-20, ATGP1670-50, ATGP1670-100, ATGP1670-250, ATGP1670-500, ATGP1670-1

Li J., et al. (1999) J Cell Biol. 147: 1391-1398; ; Li J., et al. (2003) Dev Biol. 261: 209-219.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol,1mM DTT

Cytoskeleton

NP_733778

Q9NPI5

Human

MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM