Recombinant humaan JAK2-eiwit

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Recombinant human Jak2 protein, fused to His-tag at N-terminus, was expressed in E. coli

Janus kinase 2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK10

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

18.1 kDa (157aa)

JAK2, Janus kinase 2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK10, ATGP2487-10 µg, ATGP2487-20 µg, ATGP2487-50 µg, ATGP2487-100 µg, ATGP2487-250 µg, ATGP2487-500 µg, ATGP2487-1 mg, ATGP2487-10, ATGP2487-20, ATGP2487-50, ATGP2487-100, ATGP2487-250, ATGP2487-500, ATGP2487-1

Bole-Feysot C, Goffin V, . et al. (1998) . Endocr. Rev. 19 (3) : 225-68. doi:10.1210/er.19.3.225

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Cancer

NP_004963

O60674

Human

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE SPIFWYAPES LTESKFSVAS DVWSFGVVLY ELFTYIEKSK SPPAEFMRMI GNDKQGQMIV FHLIELLKNN GRLPRPDGCP DEIYMIMTEC WNNNVNQRPS FRDLALRVDQ IRDNMAG