Recombinant humaan JDP2-eiwit

Jun dimerization protein 2, also known as JDP2, is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. This protein is involved in a variety of transcriptional responses associated with AP-1 such as uV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. JDP2 can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JuN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin. Recombinant human JDP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Jun dimerization protein 2, Jun dimerization protein 2, JuNDM2

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

21.2 kDa (187aa) confirmed by MALDI-TOF

JDP2, Jun dimerization protein 2, Jun dimerization protein 2, JuNDM2, ATGP2068-10 µg, ATGP2068-20 µg, ATGP2068-50 µg, ATGP2068-100 µg, ATGP2068-250 µg, ATGP2068-500 µg, ATGP2068-1 mg, ATGP2068-10, ATGP2068-20, ATGP2068-50, ATGP2068-100, ATGP2068-250, ATGP2068-500, ATGP2068-1

Kawaida R., et al. (2003) J. Exp. Med. 197:1029-1035; ; Jin C., et al. (2006) Nat. Struct. Mol. Biol. 13:331-338;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA, 250 mM imidazole

Epigenomics (Transcription & Translation)

NP_569736

Q8WYK2

Human

MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK