Recombinant humaan Kallikreïne 10/KLK10-eiwit

KLK10, also known as Kallikrein-10, is one of the fifteen kallikrein subfamily members. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. It is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Recombinant human KLK10 protein, fused to His-tag at N-terminus, was expressed in E. coli.

PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

29.1 kDa (266aa)

PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10, ATGP2664-10 µg, ATGP2664-20 µg, ATGP2664-50 µg, ATGP2664-100 µg, ATGP2664-250 µg, ATGP2664-500 µg, ATGP2664-1 mg, ATGP2664-010, ATGP2664-020, ATGP2664-050, ATGP2664-100, ATGP2664-250, ATGP2664-500, ATGP2664-01M

Liu XL. et al. (1996) Cancer Res. 56:3371-3379.; ; Zhang Y. et al. (2006) Biol. Chem. 387:715-721.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Cytoskeleton

NP_001070968

O43240

Human

MGSSHHHHHH SSGLVPRGSH MGSALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSN