Recombinant humaan Kallikreïne 11/KLK11-eiwit

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed. Recombinant human KLK11 protein was expressed in E. coli.

Kallikrein-11 isoform 2, Kallikrein related peptidase 11, KLK11, hK11, Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP

E.coli

Human

Non-Tagged

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

24.8 kDa (226aa)

Kallikrein11, Kallikrein 11, PRSS20, TLSP, ATGP2773-10 µg, ATGP2773-20 µg, ATGP2773-50 µg, ATGP2773-100 µg, ATGP2773-250 µg, ATGP2773-500 µg, ATGP2773-1 mg, ATGP2773-10, ATGP2773-20, ATGP2773-50, ATGP2773-100, ATGP2773-250, ATGP2773-500, ATGP2773-1

Patsis C, Yiotakis I, et al. (2012) Clin Biochem. ; ;45 (9) :623-30. doi: 10.1016.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Signal Transduction

NP_659196

Q9UBX7

Human

MIIKGFECKP HSQPWQAALF EKTRLLCGAT LIAPRWLLTA AHCLKPRYIV HLGQHNLQKE EGCEQTRTAT ESFPHPGFNN SLPNKDHRND IMLVKMASPV SITWAVRPLT LSSRCVTAGT SCLISGWGST SSPQLRLPHT LRCANITIIE HQKCENAYPG NITDTMVCAS VQEGGKDSCQ GDSGGPLVCN QSLQGIISWG QDPCAITRKP GVYTKVCKYV DWIQET