Recombinant humaan KIN17-eiwit

DNA/RNA-binding protein KIN17, also known as KIN17, is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. KIN17 is ubiqutiously expressed with the highest levels of expression in muscle, heart and testis. SV40-transformed fibroblasts overexpress KIN17, which interacts with Large T antigen and reduces T-antigen-dependent DNA replication. Recombinant human KIN17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

DNA/RNA-binding protein KIN17, BTCD, KIN17, KIN

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

47.8 kDa (416aa) confirmed by MALDI-TOF

KIN17, DNA/RNA-binding protein KIN17, BTCD, KIN17, KIN, ATGP1797-10 µg, ATGP1797-20 µg, ATGP1797-50 µg, ATGP1797-100 µg, ATGP1797-250 µg, ATGP1797-500 µg, ATGP1797-1 mg, ATGP1797-10, ATGP1797-20, ATGP1797-50, ATGP1797-100, ATGP1797-250, ATGP1797-500, ATGP1797-1

Biard D S., et al. (1997) Radiat Res. 147:42-450; ; Mazin A., et al. (1994) Nucleic Acids Res. 22: 4335-4341.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Epigenomics (Transcription & Translation)

NP_036443

O60870

Human

MGKSDFL TPKAIANRIK SKGLQKLRWY CQMCQKQCRD ENGFKCHCMS ESHQRQLLLA SENPQQFMDY FSEEFRNDFL ELLRRRFGTK RVHNNIVYNE YISHREHIHM NATQWETLTD FTKWLGREGL CKVDETPKGW YIQYIDRDPE TIRRQLELEK KKKQDLDDEE KTAKFIEEQV RRGLEGKEQE VPTFTELSRE NDEEKVTFNL SKGACSSSGA TSSKSSTLGP SALKTIGSSA SVKRKESSQS STQSKEKKKK KSALDEIMEI EEEKKRTART DYWLQPEIIV KIITKKLGEK YHKKKAIVKE VIDKYTAVVK MIDSGDKLKL DQTHLETVIP APGKRILVLN GGYRGNEGTL ESINEKTFSA TIVIETGPLK GRRVEGIQYE DISKLA