Recombinant humaan KLRG1-eiwit

KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. Recombinant human KLRG1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

17 kDa (153aa)

KLRG1, Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, ATGP1886-10 µg, ATGP1886-20 µg, ATGP1886-50 µg, ATGP1886-100 µg, ATGP1886-250 µg, ATGP1886-500 µg, ATGP1886-1 mg, ATGP1886-10, ATGP1886-20, ATGP1886-50, ATGP1886-100, ATGP1886-250, ATGP1886-500, ATGP1886-1

Schwartzkopff S, Grundemann C, et al. (2007) . J Immunol. 179 (2) :1022-9.; ; Ibegbu CC, Xu YX, et al. (2005) . J Immunol. 174 (10) :6088-94.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_005801.3

Q96E93

Human

LCQGSNY STCASCPSCP DRWMKYGNHC YYFSVEEKDW NSSLEFCLAR DSHLLVITDN QEMSLLQVFL SEAFCWIGLR NNSGWRWEDG SPLNFSRISS NSFVQTCGAI NKNGLQASSC EVPLHWVCKK VRL