
Recombinant humaan KRT17-eiwit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
KRT17, as known as keratin17, is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Recombinant human KRT17 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Keratin type I cytoskeletal 17, Keratin, type I cytoskeletal 17, K17, PC, PC2, PCHC1
E.coli
Human
His-Tag
SDS-PAGE, Denatured
0.5 mg/mL (determined by Bradford assay)
> 90% by SDS-PAGE
50.5 kDa (455aa)
KRT17, Keratin type I cytoskeletal 17, Keratin, type I cytoskeletal 17, K17, PC, PC2, PCHC1, ATGP2580-10 µg, ATGP2580-20 µg, ATGP2580-50 µg, ATGP2580-100 µg, ATGP2580-250 µg, ATGP2580-500 µg, ATGP2580-1 mg, ATGP2580-10, ATGP2580-20, ATGP2580-50, ATGP2580-100, ATGP2580-250, ATGP2580-500, ATGP2580-1
McLean WH. et al. (1995) Nat Genet. 9:273-278.; ; Troyanovsky SM. et al. (1993) Eur J Cell Biol. 59: 127-137.;
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Signal Transduction
NP_000413
Q04695
Human
MGSSHHHHHH SSGLVPRGSH MGSMTTSIRQ FTSSSSIKGS SGLGGGSSRT SCRLSGGLGA GSCRLGSAGG LGSTLGGSSY SSCYSFGSGG GYGSSFGGVD GLLAGGEKAT MQNLNDRLAS YLDKVRALEE ANTELEVKIR DWYQRQAPGP ARDYSQYYRT IEELQNKILT ATVDNANILL QIDNARLAAD DFRTKFETEQ ALRLSVEADI NGLRRVLDEL TLARADLEMQ IENLKEELAY LKKNHEEEMN ALRGQVGGEI NVEMDAAPGV DLSRILNEMR DQYEKMAEKN RKDAEDWFFS KTEELNREVA TNSELVQSGK SEISELRRTM QALEIELQSQ LSMKASLEGN LAETENRYCV QLSQIQGLIG SVEEQLAQLR CEMEQQNQEY KILLDVKTRL EQEIATYRRL LEGEDAHLTQ YKKEPVTTRQ VRTIVEEVQD GKVISSREQV HQTTR
Beschrijving
KRT17, as known as keratin17, is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in
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