Recombinant humaan L-selectine/CD62L-eiwit

SELL, also known as L-selectin, is a cell surface component that is a member of a family of adhesion/homing receptors that play important roles in lymphocyte-endothelial cell interactions. This protein mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naive and effector subsets such as regulatory T cells. Importantly, this protein has been shown to have both adhesive and signaling functions during leukocyte migration. Recombinant human SELL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L, SELL, LNHR, LYAM1

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

34.1 kDa (303aa)

L-Selectin, CD62L, L-selectin, SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, ATGP3674-10 µg, ATGP3674-20 µg, ATGP3674-50 µg, ATGP3674-100 µg, ATGP3674-250 µg, ATGP3674-500 µg, ATGP3674-1 mg, ATGP3674-10, ATGP3674-20, ATGP3674-50, ATGP3674-100, ATGP3674-250, ATGP3674-500, ATGP3674-1

Smalley DM., et al. (2005) J Cell Mol Med. 9:255-266.; ; Kohn LA., et al. (2012) Nat. Immunol. 13:963-971.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_000646

P14151

Human

Ala

WTYHYSE KPMNWQRARR FCRDNYTDLV AIQNKAEIEY LEKTLPFSRS YYWIGIRKIG GIWTWVGTNK SLTEEAENWG DGEPNNKKNK EDCVEIYIKR NKDAGKWNDD ACHKLKAALC YTASCQPWSC SGHGECVEII NNYTCNCDVG YYGPQCQFVI QCEPLEAPEL GTMDCTHPLG NFSFSSQCAF SCSEGTNLTG IEETTCGPFG NWSSPEPTCQ VIQCEPLSAP DLGIMNCSHP LASFSFTSAC TFICSEGTEL IGKKKTICES SGIWSNPSPI CQKLDKSFSM IKEGDY