Recombinant humaan LAGE3-eiwit

L antigen family member 3, also known as LAGE3, belongs to the CTAG family. Members of the LAGE/ESO gene family are clustered together on human chromosome Xq28 and have similar exon-intron structures. unlike the other family members, which are normally expressed only in testis and activated in a wide range of human tumors, LAGE3 is ubiquitously expressed in somatic tissues. This protein is also highly conserved in mouse and rat, suggesting that the encoded protein is functionally important. Recombinant human LAGE3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

L antigen family member 3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

17.2 kDa (166aa) confirmed by MALDI-TOF

LAGE3, L antigen family member 3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2, ATGP2043-10 µg, ATGP2043-20 µg, ATGP2043-50 µg, ATGP2043-100 µg, ATGP2043-250 µg, ATGP2043-500 µg, ATGP2043-1 mg, ATGP2043-10, ATGP2043-20, ATGP2043-50, ATGP2043-100, ATGP2043-250, ATGP2043-500, ATGP2043-1

Alpen B., et al. (2002) Gene. 297:141-149.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,50% glycerol, 2mM DTT

Epigenomics (Transcription & Translation)

NP_006005

Q14657

Human

MGSSHHHHHH SSGLVPRGSH MGSMRDADAD AGGGADGGDG RGGHSCRGGV DTAAAPAGGA PPAHAPGPGR DAASAARGSR MRPHIFTLSV PFPTPLEAEI AHGSLAPDAE PHQRVVGKDL TVSGRILVVR WKAEDCRLLR ISVINFLDQL SLVVRTMQRF GPPVSR