Recombinant humaan Latexine-eiwit

Latexin, a carboxypeptidase A inhibitor, is highly expressed in heart, prostate, ovary, kidney, pancrease, and colon, moderaqte or low in other tissues including brain. Latexin has no detectable sequence similarity with plant and parasite inhibitors, but it is related to a human putative tumor suppressor protein, TIG1. It is down-regulated in the presenilin-1-deficient mouse brain, thus putatively playing a role in Alzheimer's disease. Recombinant human Latexin protein was expressed in E. coli and purified by using conventional chromatography.

LXN, ECI, TCI, MuM, Endogenous carboxypeptidase inhibitor, Latexin, Latexin protein, Tissue carboxypeptidase inhibitor.

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

25.7 kDa (222aa) confirmed by MALDI-TOF

Latexin, LXN, ECI, TCI, MuM, Endogenous carboxypeptidase inhibitor, Latexin, Latexin protein, Tissue carboxypeptidase inhibitor., ATGP0277-10 µg, ATGP0277-20 µg, ATGP0277-50 µg, ATGP0277-100 µg, ATGP0277-250 µg, ATGP0277-500 µg, ATGP0277-1 mg, ATGP0277-10, ATGP0277-20, ATGP0277-50, ATGP0277-100, ATGP0277-250, ATGP0277-500, ATGP0277-1

De Haan G., et al. (2007) . Nat Genet. 39 (2) :141-2; ; Aagaard A., et al. (2005) . Structure. 13 (2) :309-17;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 10% glycerol

Enzymes & Proteases

NP_064554.2

Q9BS40

Human

MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE