Recombinant humaan LBP-eiwit

LBP, also known as Lipopolysaccharide-binding protein, is a glycoprotein member of the BPI/LBP family of lipid-binding proteins. LBP is a glycoprotein that is synthesized principally by hepatocytes. It binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. It binds to LPS to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. Recombinant human LBP, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Lipopolysaccharide-binding protein, LBP, BPIFD2, MGC22233, LCD-binding protein, OTTHUMP00000030965

HEK293

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

51.7kDa (462aa)

, ATGP3989-10 µg, ATGP3989-20 µg, ATGP3989-50 µg, ATGP3989-100 µg, ATGP3989-250 µg, ATGP3989-500 µg, ATGP3989-1 mg, ATGP3989-10, ATGP3989-20, ATGP3989-50, ATGP3989-100, ATGP3989-250, ATGP3989-500, ATGP3989-1

J. Weiss, 2003, Biochemical Society Transactions: Volume 31, part 4: 785-790.; ; Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_004130.2

P18428

Human

Ala 26