Recombinant humaan LC3A/MAP1LC3A eiwit

Microtubule-associated proteins 1A/1B light chain 3A isoform a, also known as MAP1LC3A, is one of the light chain subunits and can associate with either MAP1A or MAP1B. It plays critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes. Recombinant human MAP1LC3A protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

"Microtubule associated protein 1 light chain 3 alpha, Microtubule-associated proteins 1A/1B light chain 3A, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1A/MAP1B light chain 3 A, MAP1A, MAP1B LC3 A, MAP1BLC3, MAP1ALC3, LC3, LC3A, ATG8E "

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

15.1 kDa (128aa) confirmed by MALDI-TOF

LC3A, MAP1LC3A, Microtubule-associated protein 1A/1B light chain 3A isoform a, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, Microtubule-associated protein 1A/1B light chain 3A isoform a, ATGP0656-10 µg, ATGP0656-20 µg, ATGP0656-50 µg, ATGP0656-100 µg, ATGP0656-250 µg, ATGP0656-500 µg, ATGP0656-1 mg, ATGP0656-10, ATGP0656-20, ATGP0656-50, ATGP0656-100, ATGP0656-250, ATGP0656-500, ATGP0656-1

Schoenfeld TA., et al. (1989) J Neurosci. 9 (5) :1712-30.; ; Mann., et al. (1996) J Neurosci Res. 43:535-544.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Cancer

NP_115903.1

Q9H492

Human