Recombinant humaan Leukotrieen A4 Hydrolase/LTA4H-eiwit

LTA4H also known as Leukotriene A-4 hydrolase is a bifunctional enzyme which converts leukotriene A4 to leukotriene B4 and acts as an aminopeptidase. This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases) . It participates in arachidonic acid metabolism. Recombinant human LTA4H, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Leukotriene A-4 hydrolase isoform1, LTA4, Leukotriene A4

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

71.7 kDa (634aa)

Leukotriene A4 Hydrolase, LTA4H, Leukotriene A-4 hydrolase isoform1, LTA4, Leukotriene A4, ATGP3071-10 µg, ATGP3071-20 µg, ATGP3071-50 µg, ATGP3071-100 µg, ATGP3071-250 µg, ATGP3071-500 µg, ATGP3071-1 mg, ATGP3071-10, ATGP3071-20, ATGP3071-50, ATGP3071-100, ATGP3071-250, ATGP3071-500, ATGP3071-1

Odlander B., et al. (1991) Biochem. Biophys. 287:167-174.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Immunology

NP_000886

P09960

Human

MGSSHHHHHH SSGLVPRGSH MGSMPEIVDT CSLASPASVC RTKHLHLRCS VDFTRRTLTG TAALTVQSQE DNLRSLVLDT KDLTIEKVVI NGQEVKYALG ERQSYKGSPM EISLPIALSK NQEIVIEISF ETSPKSSALQ WLTPEQTSGK EHPYLFSQCQ AIHCRAILPC QDTPSVKLTY TAEVSVPKEL VALMSAIRDG ETPDPEDPSR KIYKFIQKVP IPCYLIALVV GALESRQIGP RTLVWSEKEQ VEKSAYEFSE TESMLKIAED LGGPYVWGQY DLLVLPPSFP YGGMENPCLT FVTPTLLAGD KSLSNVIAHE ISHSWTGNLV TNKTWDHFWL NEGHTVYLER HICGRLFGEK FRHFNALGGW GELQNSVKTF GETHPFTKLV VDLTDIDPDV AYSSVPYEKG FALLFYLEQL LGGPEIFLGF LKAYVEKFSY KSITTDDWKD FLYSYFKDKV DVLNQVDWNA WLYSPGLPPI KPNYDMTLTN ACIALSQRWI TAKEDDLNSF NATDLKDLSS HQLNEFLAQT LQRAPLPLGH IKRMQEVYNF NAINNSEIRF RWLRLCIQSK WEDAIPLALK MATEQGRMKF TRPLFKDLAA FDKSHDQAVR TYQEHKASMH PVTAMLVGKD LKVD