Recombinant humaan LIN-7A-eiwit

Lin7A, also as known as MALS1 or VELI1, belongs to the lin-7 family. This protein contains 1 L27 domain and 1 PDZ (DHR) domain. It plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Lin7A is expressed in brain, testis, kidney, placenta and liver. Recombinant human Lin7A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein lin-7 homolog A, LIN-7A, LIN7, MALS-1, TIP-33, VELI1, Mammalian lin-seven protein 1, Tax interaction protein 33, Vertebrate lin-7 homolog 1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

28.4 kDa (256aa) confirmed by MALDI-TOF

Lin7A, Protein lin-7 homolog A, LIN-7A, LIN7, MALS-1, TIP-33, VELI1, ATGP1757-10 µg, ATGP1757-20 µg, ATGP1757-50 µg, ATGP1757-100 µg, ATGP1757-250 µg, ATGP1757-500 µg, ATGP1757-1 mg, ATGP1757-10, ATGP1757-20, ATGP1757-50, ATGP1757-100, ATGP1757-250, ATGP1757-500, ATGP1757-1

Shamshiev A., et al. (2000) Immunity 13:255-264 ; ; Winau F., et al. (2004) Nat. Immunol. 5:169-174

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Signal Transduction

NP_004655

O14910

Human

MLKPSVT SAPTADMATL TVVQPLTLDR DVARAIELLE KLQESGEVPV HKLQSLKKVL QSEFCTAIRE VYQYMHETIT VNGCPEFRAR ATAKATVAAF AASEGHSHPR VVELPKTDEG LGFNVMGGKE QNSPIYISRI IPGGVAERHG GLKRGDQLLS VNGVSVEGEH HEKAVELLKA AKDSVKLVVR YTPKVLEEME ARFEKLRTAR RRQQQQLLIQ QQQQQQQQQT QQNHMS