Recombinant humaan LITAF-eiwit

Lipopolysaccharide-induced TNF-alpha factor, also known as LITAF, is a small integral membrane protein of lysosome/late endosome. LITAF mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen. Recombinant human LITAF protein, fused to His-tag at N-terminus, was expressed in E. coli.

Lipopolysaccharide-induced TNF-alpha factor, PIG7, SIMPLE

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

19.2 kDa (181aa)

LITAF, Lipopolysaccharide-induced TNF-alpha factor, PIG7, SIMPLE, ATGP1946-10 µg, ATGP1946-20 µg, ATGP1946-50 µg, ATGP1946-100 µg, ATGP1946-250 µg, ATGP1946-500 µg, ATGP1946-1 mg, ATGP1946-10, ATGP1946-20, ATGP1946-50, ATGP1946-100, ATGP1946-250, ATGP1946-500, ATGP1946-1

Atucchi A., et al. (2006) Inflamm Bowel Dis. 13 (1) :120-121.; ; Tang X., et al. (2005) Proc Natl Acad Sci uSA. 102 (14) :5132-5137.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_004853

Q99732

Human

MGSSHHHHHH SSGLVPRGSH MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN NNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L