Recombinant humaan LKB1/STK11-eiwit

SK11 is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Recombinant human STK11 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Serine/threonine-protein kinase 11, Polarization-related protein LKB1, PJS

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

51kDa (456aa)

STK11, STK 11, Serine/threonine-protein kinase 11, Serine/threonine-protein kinase, Polarization-related protein LKB1, Polarization related protein LKB1, PJS, LKB1, LKB 1, Hlkb1, ATGP2952-10 µg, ATGP2952-20 µg, ATGP2952-50 µg, ATGP2952-100 µg, ATGP2952-250 µg, ATGP2952-500 µg, ATGP2952-1 mg, ATGP2952-010, ATGP2952-020, ATGP2952-050, ATGP2952-100, ATGP2952-250, ATGP2952-500, ATGP2952-01M

Mack HI., et al. (2013) Virology 446 (1-2), 9-16

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Cell Cycle

NP_000446

Q15831

Human

MGSSHHHHHH SSGLVPRGSH MGSMEVVDPQ QLGMFTEGEL MSVGMDTFIH RIDSTEVIYQ PRRKRAKLIG KYLMGDLLGE GSYGKVKEVL DSETLCRRAV KILKKKKLRR IPNGEANVKK EIQLLRRLRH KNVIQLVDVL YNEEKQKMYM VMEYCVCGMQ EMLDSVPEKR FPVCQAHGYF CQLIDGLEYL HSQGIVHKDI KPGNLLLTTG GTLKISDLGV AEALHPFAAD DTCRTSQGSP AFQPPEIANG LDTFSGFKVD IWSAGVTLYN ITTGLYPFEG DNIYKLFENI GKGSYAIPGD CGPPLSDLLK GMLEYEPAKR FSIRQIRQHS WFRKKHPPAE APVPIPPSPD TKDRWRSMTV VPYLEDLHGA DEDEDLFDIE DDIIYTQDFT VPGQVPEEEA SHNGQRRGLP KAVCMNGTEA AQLSTKSRAE GRAPNPARKA CSASSKIRRL SACKQQ