Recombinant humaan LMX1B eiwit

LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human LMX1B protein, fused to His-tag at N-terminus, was expressed in E. coli.

LIM homeobox transcription factor 1-beta isoform 1, LIM homeobox transcription factor 1 beta, LMX1.2, NPS1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

46.5 kDa (418aa)

LMX1B, LIM homeobox transcription factor 1-beta isoform 1, LIM homeobox transcription factor 1 beta, LMX1.2, NPS1, ATGP2730-10 µg, ATGP2730-20 µg, ATGP2730-50 µg, ATGP2730-100 µg, ATGP2730-250 µg, ATGP2730-500 µg, ATGP2730-1 mg, ATGP2730-10, ATGP2730-20, ATGP2730-50, ATGP2730-100, ATGP2730-250, ATGP2730-500, ATGP2730-1

Vollrath D., Jaramillo-babb V L., et al. (1998) . Hum. Mol. Genet. 7:1091-1098

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Neuroscience

NP_002307

O60663

Human

MGSSHHHHHH SSGLVPRGSH MGSMDIATGP ESLERCFPRG QTDCAKMLDG IKMEEHALRP GPATLGVLLG SDCPHPAVCE GCQRPISDRF LMRVNESSWH EECLQCAACQ QALTTSCYFR DRKLYCKQDY QQLFAAKCSG CMEKIAPTEF VMRALECVYH LGCFCCCVCE RQLRKGDEFV LKEGQLLCKG DYEKEKDLLS SVSPDESDSV KSEDEDGDMK PAKGQGSQSK GSGDDGKDPR RPKRPRTILT TQQRRAFKAS FEVSSKPCRK VRETLAAETG LSVRVVQVWF QNQRAKMKKL ARRHQQQQEQ QNSQRLGQEV LSSRMEGMMA SYTPLAPPQQ QIVAMEQSPY GSSDPFQQGL TPPQMPGNDS IFHDIDSDTS LTSLSDCFLG SSDVGSLQAR VGNPIDRLYS MQSSYFAS