Recombinant humaan LOX-1/OLR1-eiwit

OLR1, also known as oxidized low density lipoprotein (Ox-LDL) receptor 1, is a type II membrane protein that is a member of the C-type lectin family and acts as a cell-surface receptor for Ox-LDL. Ox-LDL plays a role in early ather-osclerosis, which includes the transformation of monocyte-derived macro-phages to foam cells in atherosclerotic lesions. This protein may also trigger the activation of the NFkB signal transduction pathway.

Oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, SCARE1

E.coli

Human

Non-Tagged

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.7 kDa (216aa)

LOX1, OLR1, Oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, SCARE1, ATGP1199-10 µg, ATGP1199-20 µg, ATGP1199-50 µg, ATGP1199-100 µg, ATGP1199-250 µg, ATGP1199-500 µg, ATGP1199-1 mg, ATGP1199-10, ATGP1199-20, ATGP1199-50, ATGP1199-100, ATGP1199-250, ATGP1199-500, ATGP1199-1

Kataoka H. et al. (1999) Circulation 99: 3110-3117.; ; Cominacini L. et al. (2000) J. Biol. Chem. 275: 12633-12638.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5% glycerol, 0.4M urea

Metabolism

NP_002534

P78380

Human

MQLSQVSDLL TQEQANLTHQ KKKLEGQISA RQQAEEASQE SENELKEMIE TLARKLNEKS KEQMELHHQN LNLQETLKRV ANCSAPCPQD WIWHGENCYL FSSGSFNWEK SQEKCLSLDA KLLKINSTAD LDFIQQAISY SSFPFWMGLS RRNPSYPWLW EDGSPLMPHL FRVRGAVSQT YPSGTCAYIQ RGAVYAENCI LAAFSICQKK ANLRAQ