Recombinant humaan LRRC59-eiwit

LRRC59 is required for nuclear import of FGF1, but not that of FGF2. This proein might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. Recombinant human LRRC59 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Leucine-rich repeat-containing protein 59, Leucine rich repeat containing 59, p34, PRO1855

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

30.3 kDa (267aa) confirmed by MALDI-TOF

LRRC59, Leucine-rich repeat-containing protein 59, Leucine rich repeat containing 59, p34, PRO1855, ATGP2349-10 µg, ATGP2349-20 µg, ATGP2349-50 µg, ATGP2349-100 µg, ATGP2349-250 µg, ATGP2349-500 µg, ATGP2349-1 mg, ATGP2349-10, ATGP2349-20, ATGP2349-50, ATGP2349-100, ATGP2349-250, ATGP2349-500, ATGP2349-1

Zhen Y., et al. (2012), Traffic 13:650-664

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 2mM EDTA

Signal Transduction

NP_060979

Q96AG4

Human

MGSSHHHHHH SSGLVPRGSH MGSMTKAGSK GGNLRDKLDG NELDLSLSDL NEVPVKELAA LPKATILDLS CNKLTTLPSD FCGLTHLVKL DLSKNKLQQL PADFGRLVNL QHLDLLNNKL VTLPVSFAQL KNLKWLDLKD NPLDPVLAKV AGDCLDEKQC KQCANKVLQH MKAVQADQER ERQRRLEVER EAEKKREAKQ RAKEAQEREL RKREKAEEKE RRRKEYDALK AAKREQEKKP KKEANQAPKS KSGSRPRKPP PRKHTRS