Recombinant humaan Lumican eiwit

LUM, also known as lumican, is a member of the class II small leucine-rich proteoglycan family. It is a major component of the cornea, dermal, and muscle connective tissues. It regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and is also present in the connective tissues of other organs and embryonic corneal stroma as a glycoprotein. It may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Recombinant human LUM, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Lumican, LUM, LDC, SLRR2D

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

37.7 kDa (329aa)

Lumican, Lumican, LUM, LDC, SLRR2D, ATGP3445-10 µg, ATGP3445-20 µg, ATGP3445-50 µg, ATGP3445-100 µg, ATGP3445-250 µg, ATGP3445-500 µg, ATGP3445-1 mg, ATGP3445-10, ATGP3445-20, ATGP3445-50, ATGP3445-100, ATGP3445-250, ATGP3445-500, ATGP3445-1

Yamamoto T., et al. (2013) Oncol Rep. 30:1609-1621.; ; Saika S., et al. (2000) J Biol Chem. 275:2607-2612.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_002336

P51884

Human

Ala

ADLQYYDYDF PLSIYGQSSP NCAPECNCPE SYPSAMYCDE LKLKSVPMVP PGIKYLYLRN NQIDHIDEKA FENVTDLQWL ILDHNLLENS KIKGRVFSKL KQLKKLHINH NNLTESVGPL PKSLEDLQLT HNKITKLGSF EGLVNLTFIH LQHNRLKEDA VSAAFKGLKS LEYLDLSFNQ IARLPSGLPV SLLTLYLDNN KISNIPDEYF KRFNALQYLR LSHNELADSG IPGNSFNVSS LVELDLSYNK LKNIPTVNEN LENYYLEVNQ LEKFDIKSFC KILGPLSYSK IKHLRLDGNR ISETSLPPDM YECLRVANEV TLNHHHHHH