Recombinant humaan LYVE-1-eiwit

LYVE-1 is also known as XLKD1 and may function in lympathic hyaluronan transport and have a role in tumor metastasis. This Protein is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. It is primarily expressed on both the luminal and abluminal surfaces of lymphatic vessels but is also observed in normal liver blood sinusoids, and embryonic blood vessels. It is selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. Recombinant human LYVE-1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Lymphatic vessel endothelial hyaluronan receptor 1, CRSBP-1, HAR, LYVE-1, XLKD1, LYVE1, Lymphatic vessel endothelial hyaluronan receptor 1 CRSBP 1, CRSBP1, extracellular link domain containing 1, extracellular link domain-containing 1, hyaluronic acid receptor, LYVE 1, Lymphatic endothelium specific hyaluronan receptor

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

23.9kDa (220aa)

LYV0801, ATGP4008-10 µg, ATGP4008-20 µg, ATGP4008-50 µg, ATGP4008-100 µg, ATGP4008-250 µg, ATGP4008-500 µg, ATGP4008-1 mg, ATGP4008-10, ATGP4008-20, ATGP4008-50, ATGP4008-100, ATGP4008-250, ATGP4008-500, ATGP4008-1, ATGP4008-10 µg, ATGP4008-20 µg, ATGP4008-50 µg, ATGP4008-100 µg, ATGP4008-250 µg, ATGP4008-500 µg, ATGP4008-1 mg, ATGP4008-10, ATGP4008-20, ATGP4008-50, ATGP4008-100, ATGP4008-250, ATGP4008-500, ATGP4008-1

Chen L. et al. (2005) Invest. Ophthalmol Vis. Sci. 46:4536-4540.; ; Banerji S. et al. (1999) J. Cell Biol. 144:789-801.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Cardiovascular

NP_006682.2

Q9Y5Y7

Human

Ala

LRAEELS IQVSCRIMGI TLVSKKANQQ LNFTEAKEAC RLLGLSLAGK DQVETALKAS FETCSYGWVG DGFVVISRIS PNPKCGKNGV GVLIRKVPVS RQFAAYCYNS SDTWTNSCIP EIITTKDPIF NTQTATQTTE FIVSDSTYSV ASPYSTIPAP TTTPPAPAST SIPRRKKLIC VTEVFMETST MSTETEPFVE NKAAFKNEAA GFGG