Recombinant humaan MAGEA6-eiwit

MAGEA6 is a member of the MAGEA family, which directs the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes (CTL) . The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA6 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Melanoma-associated antigen 6, CT1.6, MAGE-3b, MAGE3B, MAGE6

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

35.9 kDa (322aa) confirmed by MALDI-TOF

MAGEA6, Melanoma-associated antigen 6, CT1.6, MAGE-3b, MAGE3B, MAGE6, ATGP1561-10 µg, ATGP1561-20 µg, ATGP1561-50 µg, ATGP1561-100 µg, ATGP1561-250 µg, ATGP1561-500 µg, ATGP1561-1 mg, ATGP1561-10, ATGP1561-20, ATGP1561-50, ATGP1561-100, ATGP1561-250, ATGP1561-500, ATGP1561-1

Kobayasshi Y., et al. (2000) J Hepatol. 32:612-617.; ; Klein C., et al. (2000) J Exp Med. 191: 1699-1708.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Cancer

NP_005354.1

P43360

Human