Recombinant humaan MAGEA8-eiwit

MAGEA8 also known as Melanoma-associated antigen 8 is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA8, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Melanoma-associated antigen 8, CT1.8, MAGE8

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

37.6 kDa (341aa) confirmed by MALDI-TOF

MAGEA8, Melanoma-associated antigen 8, CT1.8, MAGE8, ATGP3052-10 µg, ATGP3052-20 µg, ATGP3052-50 µg, ATGP3052-100 µg, ATGP3052-250 µg, ATGP3052-500 µg, ATGP3052-1 mg, ATGP3052-10, ATGP3052-20, ATGP3052-50, ATGP3052-100, ATGP3052-250, ATGP3052-500, ATGP3052-1

Serrano A., et al. (1999) Int. J. Cancer 83 (5), 664-669; ; Rogner uC., et al. (1995) Genomics 29 (3), 725-731;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Cancer

NP_001159873

P43361

Human

MLLGQKS QRYKAEEGLQ AQGEAPGLMD VQIPTAEEQK AASSSSTLIM GTLEEVTDSG SPSPPQSPEG ASSSLTVTDS TLWSQSDEGS SSNEEEGPST SPDPAHLESL FREALDEKVA ELVRFLLRKY QIKEPVTKAE MLESVIKNYK NHFPDIFSKA SECMQVIFGI DVKEVDPAGH SYILVTCLGL SYDGLLGDDQ STPKTGLLII VLGMILMEGS RAPEEAIWEA LSVMGLYDGR EHSVYWKLRK LLTQEWVQEN YLEYRQAPGS DPVRYEFLWG PRALAETSYV KVLEHVVRVN ARVRISYPSL HEEALGEEKG V