Recombinant humaan mannaanbindend lectine/MBL2-eiwit

Mannose-binding protein C, also known as MBL2, is a member of the collectin family of patternrecognition molecules. MBL2 is a secreted glycoprotein that is synthesized as a 248 amino acid precursor. The Protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. Recombinant human MBL2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Mannose binding lectin 2, MBL, Collectin 1, Mannose-binding protein, COLEC1, MBP-C, MBP1, MBP, MBL

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

18 kDa (164aa)

MBL2, Mannose-binding protein C, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, ATGP1812-10 µg, ATGP1812-20 µg, ATGP1812-50 µg, ATGP1812-100 µg, ATGP1812-250 µg, ATGP1812-500 µg, ATGP1812-1 mg, ATGP1812-10, ATGP1812-20, ATGP1812-50, ATGP1812-100, ATGP1812-250, ATGP1812-500, ATGP1812-1

Sastry K., et al. (1989) J Exp Med. 170:1175.; ; Larsen F., et al. (2004) J Biol Chem. 279:21302.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M Nacl

Immunology

NP_000233

P11226

Human

MGSSHHHHHH SSGLVPRGSH MGSAASERKA LQTEMARIKK WLTFSLGKQV GNKFFLTNGE IMTFEKVKAL CVKFQASVAT PRNAAENGAI QNLIKEEAFL GITDEKTEGQ FVDLTGNRLT YTNWNEGEPN NAGSDEDCVL LLKNGQWNDV PCSTSHLAVC EFPI