Recombinant humaan Melaan-A/MART-1-eiwit

Melanoma antigen recognized by T-cells 1, also known as MLANA, is involved in melanosome biogenesis by ensuring the stability of GPR143. This protein plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. Recombinant human MLANA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Melanoma antigen recognized by T-cells 1, MART-1, MART1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

10.4 kDa (94aa) confirmed by MALDI-TOF

Melan-A, MART1, Melanoma antigen recognized by T-cells 1, MART-1, MART1, ATGP2146-10 µg, ATGP2146-20 µg, ATGP2146-50 µg, ATGP2146-100 µg, ATGP2146-250 µg, ATGP2146-500 µg, ATGP2146-1 mg, ATGP2146-10, ATGP2146-20, ATGP2146-50, ATGP2146-100, ATGP2146-250, ATGP2146-500, ATGP2146-1

Hoashi T., et al. (2005) J. Biol. Chem. 280:14006-14016; ; Giordano F., et al. (2009) Hum. Mol. Genet. 18:4530-4545

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Cancer

NP_005502

Q16655

Human

MGSSHHHHHH SSGLVPRGSH MGSCRRRNGY RALMDKSLHV GTQCALTRRC PQEGFDHRDS KVSLQEKNCE PVVPNAPPAY EKLSAEQSPP PYSP