Recombinant humaan mesotrypsine/PRSS3-eiwit

PRSS3 is a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. Recombinant human PRSS3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Brain trypsinogen, Mesotrypsin, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin-3, Trypsin III, Trypsin IV, PRSS4, TRY3, TRY4

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

26 kDa (247aa)

PRSS3, Trypsin-3 isoform 1, MTG, PRSS4, T9, TRY3, TRY4, ATGP2255-10 µg, ATGP2255-20 µg, ATGP2255-50 µg, ATGP2255-100 µg, ATGP2255-250 µg, ATGP2255-500 µg, ATGP2255-1 mg, ATGP2255-10, ATGP2255-20, ATGP2255-50, ATGP2255-100, ATGP2255-250, ATGP2255-500, ATGP2255-1

Masson E, Le Marechal C, et al. (2008) . Pancreas. 37 (2) :227-8. ; ; Jiang G, Cao F, et al. (2010) . Gut. 59 (11) :1535-44.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cancer

NP_031369.2

P35030

Human

IVGGYTC EENSLPYQVS LNSGSHFCGG SLISEQWVVS AAHCYKTRIQ VRLGEHNIKV LEGNEQFINA AKIIRHPKYN RDTLDNDIML IKLSSPAVIN ARVSTISLPT APPAAGTECL ISGWGNTLSF GADYPDELKC LDAPVLTQAE CKASYPGKIT NSMFCVGFLE GGKDSCQRDS GGPVVCNGQL QGVVSWGHGC AWKNRPGVYT KVYNYVDWIK DTIAANS