Recombinant humaan METTL11A-eiwit

NTMT1 also known as N-terminal Xaa-Pro-Lys N-methyltrasferase1 isoform a. NTMT1 is catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the protein alpha-amine, resulting in formation of S-adenosyl-l-homocysteine and alpha-N-methylated proteins. NTMT1 is an interesting potential anticancer target because it is overexpressed in gastrointestinal cancers and plays an important role in cell mitosis. Recombinant human NTMT1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NTM1A, NTMT1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

> 95% by SDS-PAGE

28.1 kDa (248aa)

METTL11A, AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NTM1A, NTMT1, ATGP3259-10 µg, ATGP3259-20 µg, ATGP3259-50 µg, ATGP3259-100 µg, ATGP3259-250 µg, ATGP3259-500 µg, ATGP3259-1 mg, ATGP3259-10, ATGP3259-20, ATGP3259-50, ATGP3259-100, ATGP3259-250, ATGP3259-500, ATGP3259-1

Petkowski JJ., et al. (2013) Biochem J. 456 (3) : 453-462.; ; Richardson SL., et al. (2015) J Biol Chem. 290 (18) :11601-10.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Cell Cycle

NP_054783.2

Q9BV86

Human

MTSEV IEDEKQFYSK AKTYWKQIPP TVDGMLGGYG HISSIDINSS RKFLQRFLRE GPNKTGTSCA LDCGAGIGRI TKRLLLPLFR EVDMVDITED FLVQAKTYLG EEGKRVRNYF CCGLQDFTPE PDSYDVIWIQ WVIGHLTDQH LAEFLRRCKG SLRPNGIIVI KDNMAQEGVI LDDVDSSVCR DLDVVRRIIC SAGLSLLAEE RQENLPDEIY HVYSFALR