Recombinant humaan MLF1IP-eiwit

MLF1IP, as known as centromere, is a specialized chromatin domain, present throughout the cell cycle that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. It plays an important role in the correct PLK1 localization to the mitotic kinetochores. It is a scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. It also involved in transcriptional repression. Recombinant human MLF1IP protein, fused to His-tag at N-terminus, was expressed in E. coli.

Centromere protein u, CENP50, CENPu, CENPu50, KLIP1, PBIP1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

33.7 kDa (295aa)

MLF1IP, Centromere protein u, CENP50, CENPu, CENPu50, KLIP1, PBIP1, ATGP2495-10 µg, ATGP2495-20 µg, ATGP2495-50 µg, ATGP2495-100 µg, ATGP2495-250 µg, ATGP2495-500 µg, ATGP2495-1 mg, ATGP2495-10, ATGP2495-20, ATGP2495-50, ATGP2495-100, ATGP2495-250, ATGP2495-500, ATGP2495-1

Foltz DR. et al. (2006) Nat Cell Biol. 8:458-469.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Cancer

NP_078905

Q71F23

Human

TRRKVKS AEKISTQRHE VIRTTASSEL SEKPAESVTS KKTGPLSAQP SVEKENLAIE SQSKTQKKGK ISHDKRKKSR SKAIGSDTSD IVHIWCPEGM KTSDIKELNI VLPEFEKTHL EHQQRIESKV CKAAIATFYV NVKEQFIKML KESQMLTNLK RKNAKMISDI EKKRQRMIEV QDELLRLEPQ LKQLQTKYDE LKERKSSLRN AAYFLSNLKQ LYQDYSDVQA QEPNVKETYD SSSLPALLFK ARTLLGAESH LRNINHQLEK LLDQG