Recombinant humaan MLLT11-eiwit

Protein AF1q, also known as MLLT11, belongs to the Mixed-Lineage Leukemia (MLL) protein family. It is located on chromosome 11q23. MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML) . Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Recombinant human MLLT11 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Protein AF1q, AF1Q, RP11-316M1.10

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

12.4 kDa (113aa)

MLLT11, Protein AF1q, AF1Q, RP11-316M1.10, ATGP2721-10 µg, ATGP2721-20 µg, ATGP2721-50 µg, ATGP2721-100 µg, ATGP2721-250 µg, ATGP2721-500 µg, ATGP2721-1 mg, ATGP2721-10, ATGP2721-20, ATGP2721-50, ATGP2721-100, ATGP2721-250, ATGP2721-500, ATGP2721-1

Chang X Z., et al. (2008) Breast cancer Res Treat. 111: 65-78.; ; Tse W., et al. (1995) Blood. 85: 650-656.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Other

NP_006809

Q13015

Human

MGSSHHHHHH SSGLVPRGSH MGSMRDPVSS QYSSFLFWRM PIPELDLSEL EGLGLSDTAT YKVKDSSVGK MIGQATAADQ EKNPEGDGLL EYSTFNFWRA PIASIHSFEL DLL