Recombinant humaan MMP-10 eiwit

MMP10 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. MMP10 is part of a cluster of MMP genes which localize to chromosome 11q22. 3. Recombinant human MMP10 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Stromelysin-2 preproprotein, SL-2, STMY2

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

45.4 kDa (401aa)

MMP10, stromelysin-2 preproprotein, SL-2, STMY2, ATGP2537-10 µg, ATGP2537-20 µg, ATGP2537-50 µg, ATGP2537-100 µg, ATGP2537-250 µg, ATGP2537-500 µg, ATGP2537-1 mg, ATGP2537-10, ATGP2537-20, ATGP2537-50, ATGP2537-100, ATGP2537-250, ATGP2537-500, ATGP2537-1

Wojciechowski, R., et al. (2013) Ophthalmology 120 (2), 298-305 ; ; Sze, K.M., et al. (2013) Hepatology 57 (1), 131-139;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Cancer

NP_002416

P09238

Human

MGSSHHHHHH SSGLVPRGSH MGSFSSFPGM PKWRKTHLTY RIVNYTPDLP RDAVDSAIEK ALKVWEEVTP LTFSRLYEGE ADIMISFAVK EHGDFYSFDG PGHSLAHAYP PGPGLYGDIH FDDDEKWTED ASGTNLFLVA AHELGHSLGL FHSANTEALM YPLYNSFTEL AQFRLSQDDV NGIQSLYGPP PASTEEPLVP TKSVPSGSEM PAKCDPALSF DAISTLRGEY LFFKDRYFWR RSHWNPEPEF HLISAFWPSL PSYLDAAYEV NSRDTVFIFK GNEFWAIRGN EVQAGYPRGI HTLGFPPTIR KIDAAVSDKE KKKTYFFAAD KYWRFDENSQ SMEQGFPRLI ADDFPGVEPK VDAVLQAFGF FYFFSGSSQF EFDPNARMVT HILKSNSWLH C