Recombinant humaan MMP-28-eiwit

MMP28 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. MMP28 is a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described. Recombinant human MMP28 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Matrix metallopeptidase 28, EPILYSIN, MM28, MMP-28, MMP25

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

47.3 kDa (421aa)

MMP-28, MMP28, MMP25, MMP-25, MMP 28, MMP 25, MM28, Matrix metallopeptidase 28, EPILYSIN, ATGP2546-10 µg, ATGP2546-20 µg, ATGP2546-50 µg, ATGP2546-100 µg, ATGP2546-250 µg, ATGP2546-500 µg, ATGP2546-1 mg, ATGP2546-010, ATGP2546-020, ATGP2546-050, ATGP2546-100, ATGP2546-250, ATGP2546-500, ATGP2546-01M

Marchenko G.N., et al. (2001) Gene. 265:87-93; ; Lohi J., et al. (2001) J. Biol. Chem. 276:10134-10144;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cancer

NP_077278

Q9H239

Human

MGSSHHHHHH SSGLVPRGSH MGSFAKQGNK WYKQHLSYRL VNWPEHLPEP AVRGAVRAAF QLWSNVSALE FWEAPATGPA DIRLTFFQGD HNDGLGNAFD GPGGALAHAF LPRRGEAHFD QDERWSLSRR RGRNLFVVLA HEIGHTLGLT HSPAPRALMA PYYKRLGRDA LLSWDDVLAV QSLYGKPLGG SVAVQLPGKL FTDFETWDSY SPQGRRPETQ GPKYCHSSFD AITVDRQQQL YIFKGSHFWE VAADGNVSEP RPLQERWVGL PPNIEAAAVS LNDGDFYFFK GGRCWRFRGP KPVWGLPQLC RAGGLPRHPD AALFFPPLRR LILFKGARYY VLARGGLQVE PYYPRSLQDW GGIPEEVSGA LPRPDGSIIF FRDDRYWRLD QAKLQATTSG RWATELPWMG CWHANSGSAL F