Recombinant humaan MMP-9 eiwit

MMP9, also known matrix metalloproteinase-9, is one of the matrix metalloproteinases superfamily which is zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. It degrades many substrates such as gelatin, collagens, elastin and proteoglycan core protein which appears to be involved in invasive ability. This protein also plays an essential role in leukocyte migration and in bone osteoclastic resorption. It plays an important role in angiogenesis and neovascularization and so appears to be involved in the remodeling associated with malignant glioma neovascularization. Recombinant human MMP9 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Matrix metalloproteinase-9, MMP-9, CLG4B, GELB, MANDP2, Gelatinase B, 92kDa gelatinase, 92kDa type IV collagenaseANDP2, MMP-9

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

77.1 kDa (694aa)

Matrix metalloproteinase-9, MMP9, CLG4B, GELB, MANDP2, MMP-9, Gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase, ATGP3836-10 µg, ATGP3836-20 µg, ATGP3836-50 µg, ATGP3836-100 µg, ATGP3836-250 µg, ATGP3836-500 µg, ATGP3836-1 mg, ATGP3836-010, ATGP3836-020, ATGP3836-050, ATGP3836-100, ATGP3836-250, ATGP3836-500, ATGP3836-01M

Lee YD., et al, (2014) BMB Rep. 47:262-267.; ; Matin S., et al, (2018) Int J Chron Obstruct Pulmon Dis. 13:1449-1454.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_004985.2

P14780

Human

Ala20