Recombinant humaan MOBKL1B/MOB1A-eiwit

MOBKL1B, also known as MOB1B, belongs to the MOB1/phocein family. It stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1B participates in cell cycle checkpoint control and tumor inhibition. Recombinant human MOBKL1B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

MOB kinase activator 1A, Mob1 alpha, Mob1A, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, MOB1 Mps One Binder homolog A, MOB4B, MOBK1B, MOBKL1B

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

27.2 kDa (236aa) confirmed by MALDI-TOF

Mps one binder kinase activator-like 1B, MOBKL1B, MOBK1B, MOB4B, Mob1A, MOB1 Mps One Binder homolog A, Mob1 homolog 1B, Mob1 alpha, Mob1 A, MOB1, MOB kinase activator 1A, MATS1, FLJ11595, FLJ10788, C2orf6, ATGP0866-10 µg, ATGP0866-20 µg, ATGP0866-50 µg, ATGP0866-100 µg, ATGP0866-250 µg, ATGP0866-500 µg, ATGP0866-1 mg, ATGP0866-010, ATGP0866-020, ATGP0866-050, ATGP0866-100, ATGP0866-250, ATGP0866-500, ATGP0866-01M

Lai ZC., et al. (2005) Cell. 120 (5) :675-85.; ; Bichsel SJ., et al. (2004) J Biol Chem. 279 (34) :35228-35.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol

Cancer

NP_060691

Q9H8S9

Human

MGSSHHHHHH SSGLVPRGSH MSFLFSSRSS KTFKPKKNIP EGSHQYELLK HAEATLGSGN LRQAVMLPEG EDLNEWIAVN TVDFFNQINM LYGTITEFCT EASCPVMSAG PRYEYHWADG TNIKKPIKCS APKYIDYLMT WVQDQLDDET LFPSKIGVPF PKNFMSVAKT ILKRLFRVYA HIYHQHFDSV MQLQEEAHLN TSFKHFIFFV QEFNLIDRRE LAPLQELIEK LGSKDR