Recombinant humaan MORF4L2-eiwit

MORF4L2 is a member of the mortality factor (MORF) family of transcriptional regulator that is involved in cell growth, regulation and senescence. This protein localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. It interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. It also has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue. Recombinant human MORF4L2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Mortality factor 4-like protein 2, KIAA0026, MORFL2, MRGX

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

34.4 kDa (308aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

MORF4L2, Mortality factor 4-like protein 2, KIAA0026, MORFL2, MRGX, ATGP0987-10 µg, ATGP0987-20 µg, ATGP0987-50 µg, ATGP0987-100 µg, ATGP0987-250 µg, ATGP0987-500 µg, ATGP0987-1 mg, ATGP0987-10, ATGP0987-20, ATGP0987-50, ATGP0987-100, ATGP0987-250, ATGP0987-500, ATGP0987-1

Nomura N., et al. (1995), DNA Res.. 1: 27-35.; ; Tominaga K, et al. (2003) . J. Biol. Chem.. 278: 49618-49624.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Cancer

NP_036418

Q15014

Human

MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL