Recombinant humaan MREG-eiwit

Melanoregulin, also known as MREG, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG is expressed in photoreceptor cells as two isoforms due to alternative splicing. MREG interacts with Peripherin-2, a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. Recombinant human MREG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Melanoregulin, DSu, WDT2

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

> 90% by SDS-PAGE

27.3 kDa (237aa) confirmed by MALDI-TOF

MREG, Melanoregulin, DSu, WDT2, ATGP2582-10 µg, ATGP2582-20 µg, ATGP2582-50 µg, ATGP2582-100 µg, ATGP2582-250 µg, ATGP2582-500 µg, ATGP2582-1 mg, ATGP2582-10, ATGP2582-20, ATGP2582-50, ATGP2582-100, ATGP2582-250, ATGP2582-500, ATGP2582-1

Loewen C J., et al. (2003) Mol Biol Cell. 14: 3400-3413.; ; Roof D J., et al. (1982) J Cell Biol. 95: 501-509.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Other

NP_060470.2

Q8N565

Human

MGLRDWL RTVCCCCGCE CLEERALPEK EPLVSDNNPY SSFGATLVRD DEKNLWSMPH DVSHTEADDD RTLYNLIVIR NQQAKDSEEW QKLNYDIHTL RQVRREVRNR WKCILEDLGF QKEADSLLSV TKLSTISDSK NTRKAREMLL KLAEETNIFP TSWELSERYL FVVDRLIALD AAEEFFKLAR RTYPKKPGVP CLADGQKELH YLPFPSP