Recombinant humaan MRM1-eiwit

Mitochondrial rRNA methyltransferase 1 homolog, also known as MRM1, probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S) . Recombinant human MRM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Mitochondrial rRNA methyltransferase 1 homolog, FLJ22578, Mitochondrial large ribosomal RNA ribose methylase

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

38.8 kDa (356aa) confirmed by MALDI-TOF

MRM1, Mitochondrial rRNA methyltransferase 1 homolog, FLJ22578, Mitochondrial large ribosomal RNA ribose methylase, ATGP2038-10 µg, ATGP2038-20 µg, ATGP2038-50 µg, ATGP2038-100 µg, ATGP2038-250 µg, ATGP2038-500 µg, ATGP2038-1 mg, ATGP2038-10, ATGP2038-20, ATGP2038-50, ATGP2038-100, ATGP2038-250, ATGP2038-500, ATGP2038-1

Ota T., et al. (2004) Nat. Genet. 36:40-45

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT, 0.1mM PMSF

Epigenomics (Transcription & Translation)

NP_079140

Q6IN84

Human

SHAARHG ERPGGEELSR LLLDDLVPTS RLELLFGMTP CLLALQAARR SVARLLLQAG KAGLQGKRAE LLRMAEARDI PVLRPRRQKL DTMCRYQVHQ GVCMEVSPLR PRPWREAGEA SPGDDPQQLW LVLDGIQDPR NFGAVLRSAH FLGVDKVITS RRNSCPLTPV VSKSSAGAME VMDVFSTDDL TGFLQTKAQQ GWLVAGTVGC PSTEDPQSSE IPIMSCLEFL WERPTLLVLG NEGSGLSQEV QASCQLLLTI LPRRQLPPGL ESLNVSVAAG ILLHSICSQR KGFPTEGERR QLLQDPQEPS ARSEGLSMAQ HPGLSSGPEK ERQNEG