Recombinant humaan MXD3-eiwit

MXD3 is a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described. Recombinant human MXD3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Max dimerization protein 3, BHLHC13, MAD3, MYX

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

25.9 kDa (229aa)

MXD3, Max dimerization protein 3, BHLHC13, MAD3, MYX, ATGP1957-10 µg, ATGP1957-20 µg, ATGP1957-50 µg, ATGP1957-100 µg, ATGP1957-250 µg, ATGP1957-500 µg, ATGP1957-1 mg, ATGP1957-10, ATGP1957-20, ATGP1957-50, ATGP1957-100, ATGP1957-250, ATGP1957-500, ATGP1957-1

Yun JS, Rust JM, et al. (2007) . Mol Cell Biol. 27 (23) :8178-89.; ; Barisone GA, Yun JS, et al. (2008) . Cell Cycle. 7 (4) :423-7.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_112590

Q9BW11

Human

MGSSHHHHHH SSGLVPRGSH MGSMEPLASN IQVLLQAAEF LERREREAEH GYASLCPHRS PGPIHRRKKR PPQAPGAQDS GRSVHNELEK RRRAQLKRCL ERLKQQMPLG ADCARYTTLS LLRRARMHIQ KLEDQEQRAR QLKERLRSKQ QSLQRQLEQL RGLAGAAERE RLRADSLDSS GLSSERSDSD QEELEVDVES LVFGGEAELL RGFVAGQEHS YSHGGGAWL