Recombinant humaan MYCBP-eiwit

MYCBP, also known as c-Myc binding protein, binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. It translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. It has also been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP in spermatogenesis. Recombinant human MYCBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

C-Myc-binding protein, AMY-1, FLJ41056

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

14.1 kDa (123aa) confirmed by MALDI-TOF

MYCBP, C-Myc-binding protein, AMY-1, FLJ41056, ATGP1226-10 µg, ATGP1226-20 µg, ATGP1226-50 µg, ATGP1226-100 µg, ATGP1226-250 µg, ATGP1226-500 µg, ATGP1226-1 mg, ATGP1226-10, ATGP1226-20, ATGP1226-50, ATGP1226-100, ATGP1226-250, ATGP1226-500, ATGP1226-1

Furusawa M. et al. (2001) J. Biol. Chem. 276: 36647-36651.; ; Yukitake H. et al. (2002) J. Biol. Chem. 277: 45480-45492.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Signal Transduction

NP_036465

Q99417

Human

MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP EIELLRLELA EMKEKYEAIV EENKKLKAKL AQYEPPQEEK RAE