Recombinant humaan Myostatine/GDF-8 eiwit

MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Recombinant human MSTN, fused to His-tag at N-terminus, was expressed in E. coli.

Growth/differentiation factor 8, Myostatin, GDF8, MSLHP, MSTN

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

15.1 kDa (134aa)

MSTN, Growth/differentiation factor 8, Growth/differentiation factor 8, Myostatin, GDF8, MSLHP, ATGP2917-10 µg, ATGP2917-20 µg, ATGP2917-50 µg, ATGP2917-100 µg, ATGP2917-250 µg, ATGP2917-500 µg, ATGP2917-1 mg, ATGP2917-10, ATGP2917-20, ATGP2917-50, ATGP2917-100, ATGP2917-250, ATGP2917-500, ATGP2917-1

Hill J.J., et al. (2003) Mol. Endocrinol. 17:1144-1154

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_005250

O14793

Human

HMDFGLD CDEHSTESRC CRYPLTVDFE AFGWDWIIAP KRYKANYCSG ECEFVFLQKY PHTHLVHQAN PRGSAGPCCT PTKMSPINML YFNGKEQIIY GKIPAMVVDR CGCS