Recombinant humaan NFKBID-eiwit

NF-kappa-B inhibitor delta, also known as NFKBID, is a member of the IkB family of proteins can be divided into four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon) . NFKBID plays a role in the regulation of both inflammatory responses and cytokine, IL-2 and IL-6 expression via NFkB activity. Existing as three alternatively spliced isoforms, NFKBID associates with RelB, NFkB p50 and NFkB p65 in nucleus, and is thought to assist in thymocyte selection in response to TCR induction. Recombinant human NFKBID protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

NF-kappa-B inhibitor delta, IkappaBNS, TA-NFKBH

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

35.9 kDa (336aa) confirmed by MALDI-TOF

NFKBID, NF-kappa-B inhibitor delta, IkappaBNS, TA-NFKBH, ATGP2305-10 µg, ATGP2305-20 µg, ATGP2305-50 µg, ATGP2305-100 µg, ATGP2305-250 µg, ATGP2305-500 µg, ATGP2305-1 mg, ATGP2305-10, ATGP2305-20, ATGP2305-50, ATGP2305-100, ATGP2305-250, ATGP2305-500, ATGP2305-1

Wand L., et al. (2000) Clin Cancer Res. 6:2988-2993.; ; Trowsdale J., et al. (2001) Immunol Rev. 181:20-38.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Signal Transduction

NP_640332.1

Q8NI38

Human

MEAGPWR VSAPPSGPPQ FPAVVPGPSL EVARAHMLAL GPQQLLAQDE EGDTLLHLFA ARGLRWAAYA AAEVLQVYRR LDIREHKGKT PLLVAAAANQ PLIVEDLLNL GAEPNAADHQ GRSVLHVAAT YGLPGVLLAV LNSGVQVDLE ARDFEGLTPL HTAILALNVA MRPSDLCPRV LSTQARDRLD CVHMLLQMGA NHTSQEIKSN KTVLHLAVQA ANPTLVQLLL ELPRGDLRTF VNMKAHGNTA LHMAAALPPG PAQEAIVRHL LAAGADPTLR NLENEQPVHL LRPGPGPEGL RQLLKRSRVA PPGLSS