Recombinant humaan niereiwit

REN, also known as renin, is a member of the peptidase A1 family. It is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. It is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Recombinant human REN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Renin, REN, HNFJ2, Angiotensin forming enzyme, Angiotensin forming enzyme precursor, Angiotensinogenase, Angiotensinogenase precursor, FLJ10761, HNFJ2, REN, Ren1, RENI_HUMAN, Renin, Renin precursor renal

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

43.3 kDa (391aa)

Renin, Renin , REN, HNFJ2, Angiotensin forming enzyme, Angiotensin forming enzyme precursor, Angiotensinogenase, Angiotensinogenase precursor, FLJ10761, HNFJ2, REN, Ren1, RENI_HUMAN, Renin, Renin precursor renal, ATGP3412-10 µg, ATGP3412-20 µg, ATGP3412-50 µg, ATGP3412-100 µg, ATGP3412-250 µg, ATGP3412-500 µg, ATGP3412-1 mg, ATGP3412-10, ATGP3412-20, ATGP3412-50, ATGP3412-100, ATGP3412-250, ATGP3412-500, ATGP3412-1

Nguyen G., et al. (2014) Hypertension. 63:297-302.; ; Nabi AH., et al. (2012) Biochem Biophys Res Commun. 428:506-511.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_000528

P00797

Human

Leu24