Recombinant humaan NIPP1/PPP1R8-eiwit

PPP1R8, also as known as NIPP-1, is the RNA-binding subunit of a major species of protein phosphatase-1 in the nucleus. This enzyme is inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1) . It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. Recombinant human PPP1R8 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Nuclear inhibitor of protein phosphatase 1, ARD-1, ARD1, NIPP-1, NIPP1, PRO2047

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.5 kDa (359aa) confirmed by MALDI-TOF

PPP1R8, Nuclear inhibitor of protein phosphatase 1, ARD-1, ARD1, NIPP-1, NIPP1, PRO2047, ATGP1703-10 µg, ATGP1703-20 µg, ATGP1703-50 µg, ATGP1703-100 µg, ATGP1703-250 µg, ATGP1703-500 µg, ATGP1703-1 mg, ATGP1703-10, ATGP1703-20, ATGP1703-50, ATGP1703-100, ATGP1703-250, ATGP1703-500, ATGP1703-1

Jin Q., et al. (1999) Biochem. J. 342:13-19; ; Beullens M., et al. (2000) Biochem. J. 352:651-658

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 2mM DTT

Signal Transduction

NP_054829.2

Q12972

Human